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E K Rowinsky Selected Research

1843U89

7/2001A phase I and pharmacokinetic study of 1843U89, a noncompetitive inhibitor of thymidylate synthase, in patients with advanced solid malignancies.

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E K Rowinsky Research Topics

Disease

24Neoplasms (Cancer)
01/2011 - 01/2000
5Colorectal Neoplasms (Colorectal Cancer)
02/2011 - 04/2000
5Diarrhea
02/2006 - 01/2000
4Neutropenia
07/2001 - 01/2000
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
09/2011 - 12/2000
3Lung Neoplasms (Lung Cancer)
01/2001 - 03/2000
2Hypersensitivity (Allergy)
12/2004 - 05/2001
2Breast Neoplasms (Breast Cancer)
08/2001 - 05/2001
2Mucositis
07/2001 - 03/2000
2Fever (Fevers)
05/2001 - 01/2000
2Carcinoma (Carcinomatosis)
02/2001 - 12/2000
1Exanthema (Rash)
09/2011
1Mouth Neoplasms (Oral Cancer)
01/2011
1Head and Neck Neoplasms (Head and Neck Cancer)
04/2007
1Squamous Cell Carcinoma of Head and Neck
04/2007
1Febrile Neutropenia
02/2006
1Hematologic Neoplasms (Hematological Malignancy)
05/2003
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
08/2001
1Heart Failure
08/2001
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
08/2001
1Ovarian Neoplasms (Ovarian Cancer)
06/2001
1Sarcoma (Soft Tissue Sarcoma)
06/2001
1Hepatocellular Carcinoma (Hepatoma)
01/2001
1Bronchogenic Carcinoma
01/2001
1Pancreatic Neoplasms (Pancreatic Cancer)
12/2000
1Adenocarcinoma
04/2000

Drug/Important Bio-Agent (IBA)

4ErbB Receptors (EGF Receptor)IBA
02/2011 - 07/2001
4Biological ProductsIBA
04/2007 - 12/2000
4Pharmaceutical PreparationsIBA
12/2001 - 12/2000
4Paclitaxel (Taxol)FDA LinkGeneric
08/2001 - 09/2000
4Fluorouracil (Carac)FDA LinkGeneric
05/2001 - 01/2000
3Erlotinib Hydrochloride (CP 358,774)FDA Link
09/2011 - 07/2001
3Monoclonal AntibodiesIBA
02/2011 - 12/2004
3Proteins (Proteins, Gene)FDA Link
02/2006 - 12/2000
3Cytotoxins (Cytolysins)IBA
05/2003 - 01/2000
2Cetuximab (Erbitux)FDA Link
02/2011 - 01/2011
2DNA (Deoxyribonucleic Acid)IBA
01/2011 - 05/2003
2Irinotecan (Camptosar)FDA LinkGeneric
02/2006 - 09/2000
2Doxorubicin (Adriamycin)FDA LinkGeneric
08/2001 - 06/2001
2PlatinumIBA
02/2001 - 09/2000
2Antineoplastic Agents (Antineoplastics)IBA
01/2001 - 01/2000
2irofulvenIBA
12/2000 - 12/2000
2eniluracilIBA
10/2000 - 02/2000
13' Untranslated Regions (3' UTR)IBA
01/2011
1Formaldehyde (Formol)FDA Link
01/2011
1MicroRNAs (MicroRNA)IBA
01/2011
1ParaffinIBA
01/2011
1thiamine triphosphorate (TTP)IBA
04/2007
1Antisense OligonucleotidesIBA
02/2006
1Messenger RNA (mRNA)IBA
02/2006
1oblimersen (G3139)IBA
02/2006
1Antigen-Antibody Complex (Immune Complex)IBA
12/2004
1mAb-AR20.5IBA
12/2004
1AntigensIBA
12/2004
1bizelesinIBA
05/2003
1L 778,123IBA
12/2001
1TransferasesIBA
12/2001
1penclomedineIBA
09/2001
1Docetaxel (Taxotere)FDA Link
08/2001
1AnthracyclinesIBA
08/2001
14-phenylbutyric acid (Buphenyl)FDA Link
08/2001
1Folic Acid (Vitamin M)FDA LinkGeneric
07/2001
11843U89IBA
07/2001
1Thymidylate SynthaseIBA
07/2001
1Tyrosine Kinase InhibitorsIBA
07/2001
1Etoposide (VP 16)FDA LinkGeneric
06/2001
1becatecarin (XL 119)IBA
06/2001
1Capecitabine (Xeloda)FDA Link
05/2001
17-methylthiomethylpaclitaxel (BMS 184476)IBA
05/2001
1Thymidine PhosphorylaseIBA
05/2001
1A-Form DNA (A-DNA)IBA
02/2001
1taxaneIBA
02/2001
1furanIBA
01/2001
1Epoxy Compounds (Epoxides)IBA
01/2001
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
01/2001
14-ipomeanolIBA
01/2001
1Mixed Function Oxygenases (Monooxygenases)IBA
01/2001
1MacrolidesIBA
12/2000
1EstersIBA
12/2000
1temsirolimusFDA Link
12/2000
1Sirolimus (Rapamycin)FDA Link
12/2000
1Immunosuppressive Agents (Immunosuppressants)IBA
12/2000
1Topotecan (Hycamtin)FDA LinkGeneric
12/2000
19 alpha,11 alpha,15 alpha- trihydroxy- 16- phenoxy- 17,18,19,20- tetranorprosta- 4,5,13- trienoic acid (TPT)IBA
12/2000
1GemcitabineFDA Link
12/2000
1vesnarinoneIBA
12/2000
1TabletsIBA
10/2000
1Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA
10/2000
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
09/2000
1Cyclosporine (Ciclosporin)FDA LinkGeneric
09/2000
1Cytochrome P-450 CYP3AIBA
09/2000
1CamptothecinIBA
09/2000
1exatecan (DX 8951f)IBA
09/2000
1Folic Acid AntagonistsIBA
04/2000
1Pemetrexed (MTA)FDA Link
04/2000
1Vincristine (Oncovin)FDA LinkGeneric
03/2000
1rhizoxinIBA
03/2000

Therapy/Procedure

4Therapeutics
02/2011 - 01/2000
3Intravenous Infusions
12/2004 - 01/2000
1Premedication
05/2001